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Hyperthyroidism medication6/25/2023 ![]() For an overview of drug-associated agranulocytosis, see Antithyroid-drug-induced agranulocytosis complicated by life-threatening infections. Routine monitoring of the white blood count is generally not helpful as the low white blood count tends to develop rapidly and precipitously, and not gradually. A warning sign of a problem with your white blood cells is the development of a sore throat, fever, or other indications of severe infection, which should prompt the patient to see their physician and obtain a white blood count test. Agranulocytosis is estimated to occur in ~1:400 patients. Side effects of PTU are rare, and may range from rash, itching, or hives, to more severe conditions such as agranulocytosis (the white blood cell count decreases or disappears, leading to increased risk of infection). Patients with reduced kidney function or kidney failure often require a reduced dose of PTU. More severe hyperthyroidism may require initial treatment with higher doses of PTU. Given the short half life of PTU it usually needs to be taken in multiple daily divided doses. The initial dosing requirements depend in part on the severity of the hyperthyroidism present, and range from 100-400 mg daily in most patients. Some patients experience a bit of nausea, or mild stomach upset and many patients find that PTU leaves a bitter aftertaste. In patients with Grave's Disease (GD), PTU likely also exerts a beneficial effect on the immune disturbance underlying the development of GD, as discontinuation of PTU after an appropriate treatment course (12-24 months for most patients) is frequently association with disease remission, which may be long lasting or permanent. Propylthiouracil (PTU) PTU, used for the treatment of hyperthyroidism, exerts its actions by decreasing thyroid hormone synthesis, and by blocking the conversion of thyroxine (T4) to triiodothyronine (T3). Medications used to treat Hyperthyroidism Medications used for the Treatment of Hyperthyroidism » FOLLOW-UP FOR THYROID CANCER PATIENTSĬlick here for Frequently Asked Questions on. ![]() » PSYCHOLOGICAL IMPACT OF A THYROID CANCER DIAGNOSIS.
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